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Article

Role of the lytic repressor in prophage induction of phage lambda as analyzed by a module-replacement approach.

Proceedings of the National Academy of Sciences of the United States of America - 21 Mar 2006

Atsumi Shota, Little John W

Abstract excerpt

Using a module exchange approach, we have tested a long-standing model for the role of Cro repressor in lambda prophage induction. This epigenetic switch from lysogeny to the lytic state occurs on activation of the host SOS system, which leads to specific cleavage of CI repressor. It has been proposed that Cro repressor, which operates during lytic growth and which we shall term the lytic repressor, is crucial to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16537413
DOI: 10.1073/pnas.0511117103
PMCID: PMC1450210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the lytic repressor in prophage induction of phage lambda as analyzed by a module-replacement approach.PMID 16537413Read ↗

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