Article
The Cro-like Apl repressor of coliphage 186 is required for prophage excision and binds near the phage attachment site.
Molecular microbiology - 1 Dec 1993
Dodd I B, Reed M R, Egan J B
Abstract excerpt
The Apl protein of the temperature coliphage 186 represses transcription of the immunity repressor gene and down-regulates lytic transcription. It is shown here that an apl- mutant is competent for lytic development and establishes lysogeny normally but is defective in excision of the prophage. T...
Topics
- Attachment Sites, Microbiological
- Base Sequence
- Binding Sites
- Chromosome Mapping
- Coliphages
- DNA, Viral
- DNA-Binding Proteins
- Gene Deletion
- Genes, Viral
- Molecular Sequence Data
- Mutation
- Recombination, Genetic
- Repressor Proteins
- Transcription, Genetic
- Viral Proteins
- Viral Regulatory and Accessory Proteins
- Virus Activation