Article
The Cro-like Apl repressor of coliphage 186 is required for prophage excision and binds near the phage attachment site.
Molecular microbiology - 1 Dec 1993
Dodd I B, Reed M R, Egan J B
Abstract excerpt
The Apl protein of the temperature coliphage 186 represses transcription of the immunity repressor gene and down-regulates lytic transcription. It is shown here that an apl- mutant is competent for lytic development and establishes lysogeny normally but is defective in excision of the prophage. The Apl protein binds between the lytic and lysogenic promoters and also near the phage attachment site, suggesting that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.