Article
PepA and ArgR do not regulate Cre recombination at the bacteriophage P1 loxP site.
Plasmid - 1 Mar 2008
MacDonald Alasdair I, Lu Yangjie, Kilbride Elizabeth A, Akopian Aram, Colloms Sean D
Abstract excerpt
In the lysogenic state, bacteriophage P1 is maintained as a low copy-number circular plasmid. Site-specific recombination at loxP by the phage-encoded Cre protein keeps P1 monomeric, thus helping to ensure stable plasmid inheritance. Two Escherichia coli DNA-binding proteins, PepA and ArgR, were recently reported to be necessary for maintenance or establishment of P1 lysogeny. PepA and ArgR bind to regulatory DNA...
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