Article
An operator associated with autoregulation of the repressor gene in actinophage phiC31 is found in highly conserved copies in intergenic regions in the phage genome.
Nucleic acids research - 11 Mar 1994
Ingham C J, Owen C E, Wilson S E, Hunter I S, Smith M C
Abstract excerpt
Previous reports have suggested that the repressor gene, c, of phiC31 is autoregulated and that likely operators are conserved inverted repeat sequences (CIRs1&2) located just upstream of the promoters, cp1 and cp2. Evidence is now presented that the CIRs 1&2 are indeed binding sites for one of the three inframe, N-terminally different protein isoforms of 42, 54 and 74 kDa produced by the c gene. A cp1-aphII...
Topics
- Bacteriophages
- Base Sequence
- Blotting, Southern
- Conserved Sequence
- DNA, Viral
- Gene Expression Regulation, Viral
- Genome, Viral
- Introns
- Molecular Sequence Data
- Mutation
- Operator Regions, Genetic