Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Growth ability of auxiliary gene mutants of human immunodeficiency virus types 1 and 2 in unstimulated peripheral blood mononuclear cells.

Archives of virology - 1 Jan 1997

Tokunaga K, Ishimoto A, Ikuta K, Adachi A

Abstract excerpt

Mutational studies on the Vif, Vpr, Vpu, Vpx, and Nef genes of human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) were performed to evaluate their biological functions in natural target cells. For this purpose, replication properties of mutant viruses derived from HIV-1 NL strain and HIV-2 GH strain in unstimulated peripheral blood mononuclear cells were determined. Vif- viruses of both HIV-1 and HIV-2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Genes, Viral
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Leukocytes, Mononuclear

Share to Mutation

Share to Virus Replication

Source

Identifiers

PMID: 9155882
DOI: 10.1007/s007050050068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Growth ability of auxiliary gene mutants of human immunodeficiency virus types 1 and 2 in unstimulated peripheral blood mononuclear cells.PMID 9155882Read ↗

Growth ability of human immunodeficiency virus type 1 auxiliary gene mutants in primary blood macrophage cultures.Semantic proximity Read ↗

Biological characterization of human immunodeficiency virus type 1 and type 2 mutants in human peripheral blood mononuclear cells.Semantic proximity Read ↗

Distinct Effects in Primary Macrophages and Lymphocytes of the Human Immunodeficiency Virus Type 1 Accessory Genes vpr, vpu, and nef: Mutational Analysis of a Primary HIV-1 IsolateSemantic proximity Read ↗

Construction and In Vitro Properties of HIV-1 Mutants with Deletions in "Nonessential" GenesSemantic proximity Read ↗

Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.Semantic proximity Read ↗

Human immunodeficiency virus Vpx is required for the early phase of replication in peripheral blood mononuclear cells.Semantic proximity Read ↗

The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophageSemantic proximity Read ↗

Analysis of the cell-dependent replication potentials of human immunodeficiency virus type 1 vif mutants.Semantic proximity Read ↗

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.Semantic proximity Read ↗

Growth characteristics of T-cell tropic HIV-1 vpu gene mutants in human peripheral blood mononuclear cells.Semantic proximity Read ↗

Essential role of vif in establishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages.Semantic proximity Read ↗

Growth characteristics of SHIV without the vpu gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.