Article
Growth characteristics of T-cell tropic HIV-1 vpu gene mutants in human peripheral blood mononuclear cells.
The journal of medical investigation : JMI - 1 Feb 1999
Iida S, Fukumori T, Oshima Y, Koyama A H, Adachi A
Abstract excerpt
A mutant designated NL-E65, which lacks the expression of entire vpu gene, was constructed from T-cell tropic wild-type (wt) human immunodeficiency virus type 1 (HIV-1) clone and monitored for its replication property in human cells, along with a mutant NL-Ss which expresses a C-terminal truncated Vpu. The mutant NL-Ss could grow in two cell lines and in all peripheral blood mononuclear cell (PBMC) preparations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.