Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.

Journal of virology - 1 Jun 1995

Reddy T R, Kraus G, Yamada O, Looney D J, Suhasini M, Wong-Staal F

Abstract excerpt

Virion infectivity factor (vif), a gene found in all lentiviruses, plays an essential role in virus replication in certain target cells. We examined the replication competence of the human immunodeficiency virus type 2 (HIV-2) vif mutant in different T-cell lines and primary cells in comparison with that of the HIV-1 vif mutant. Both mutant viruses were unable to replicate in peripheral blood-derived mononuclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Genetic Complementation Test

Share to Molecular Sequence Data

Share to Mutation

Share to Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 7745702
DOI: 10.1128/JVI.69.6.3549-3553.1995
PMCID: PMC189069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.PMID 7745702Read ↗

Functional Analysis of Vif Protein Shows Less Restriction of Human Immunodeficiency Virus Type 2 by APOBEC3GSemantic proximity Read ↗

Analysis of the cell-dependent replication potentials of human immunodeficiency virus type 1 vif mutants.Semantic proximity Read ↗

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytesSemantic proximity Read ↗

Biological characterization of human immunodeficiency virus type 1 and type 2 mutants in human peripheral blood mononuclear cells.Semantic proximity Read ↗

Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells.Semantic proximity Read ↗

The requirement for Vif of SIVmac is cell-type dependent.Semantic proximity Read ↗

Cell-dependent function of HIV-1 Vif for virus replication (Review).Semantic proximity Read ↗

Tumultuous Relationship between the Human Immunodeficiency Virus Type 1 Viral Infectivity Factor (Vif) and the Human APOBEC-3G and APOBEC-3F Restriction FactorsSemantic proximity Read ↗

Complementation of vif-defective human immunodeficiency virus type 1 by primate, but not nonprimate, lentivirus vif genesSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Vif Protein Is an Integral Component of an mRNP Complex of Viral RNA and Could Be Involved in the Viral RNA Folding and Packaging ProcessSemantic proximity Read ↗

The Vif accessory protein alters the cell cycle of human immunodeficiency virus type 1 infected cells.Semantic proximity Read ↗

Comprehensive Investigation of the Molecular Defect in vif -Deficient Human Immunodeficiency Virus Type 1 VirionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.