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Article

DPC4 gene mutation in colitis associated neoplasia.

Gut - 1 Jan 1997

Hoque A T, Hahn S A, Schutte M, Kern S E

Abstract excerpt

BACKGROUND: Colitis associated dysplasia and cancer often have deletions involving the long arm of chromosome 18q, suggesting the location of a tumour suppressor gene critical for their tumorigenesis. The DPC4 gene, which is genetically inactivated in pancreatic and other cancers, has recently been described. AIM: Because DPC4 is located at 18q21.1, the hypothesis that it could be a mutated tumour suppressor gene...

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Identifiers

PMID: 9155588
DOI: 10.1136/gut.40.1.120
PMCID: PMC1027020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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DPC4 gene mutation in colitis associated neoplasia.PMID 9155588Read ↗

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1.Semantic proximity Read ↗

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Status of the DPC4 tumor suppressor gene in sporadic colon adenocarcinoma of Croatian patients: identification of a novel somatic mutation.Semantic proximity Read ↗

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Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas.Semantic proximity Read ↗

Loss of DPC4 expression and its correlation with clinicopathological parameters in pancreatic carcinoma.Semantic proximity Read ↗

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