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Article

Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma.

Cancer research - 1 Oct 1996

Barrett M T, Schutte M, Kern S E, Reid B J

Abstract excerpt

DPC4, a recently cloned gene located on 18q2l.l, is inactivated in almost one half of pancreatic adenocarcinomas. To determine whether DPC4 inactivation is involved in esophageal adenocarcinoma, we have analyzed aneuploid populations from biopsies of 35 patients with Barrett's esophagus who had premalignant epithelium, adenocarcinoma, or both. Sixteen of 35 patients (46%) had allelic loss at l8q21.1, including 7...

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PMID: 8813122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma.PMID 8813122Read ↗

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