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Article

Loss of DPC4 expression and its correlation with clinicopathological parameters in pancreatic carcinoma.

World journal of gastroenterology - 1 Dec 2003

Hua Zhan, Zhang Yuan-Chun, Hu Xiao-Ming, Jia Zhen-Geng

Abstract excerpt

AIM: DPC4 is a tumor suppressor gene on chromosome 18q21.1 that has high mutant frequencies in pancreatic carcinogenesis. The purpose of this study was to investigate the role of DPC4 alterations in tumorigenesis and progression of pancreatic carcinomas. METHODS: We studied the immunohistochemical markers of DPC4 in 34 adenocarcinomas and 16 nonmalignant specimens from the pancreas. The 16 nonmalignant specimens...

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Source

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Identifiers

PMID: 14669329
DOI: 10.3748/wjg.v9.i12.2764
PMCID: PMC4612048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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