Article
Cold-adapted poliovirus mutants bypass a postentry replication block.
Journal of virology - 1 Jun 1997
Dove A W, Racaniello V R
Abstract excerpt
In the current model of poliovirus entry, the initial interaction of the native virion with its cellular receptor is followed by a transition to an altered form, which then acts as an intermediate in viral entry. While the native virion sediments at 160S in a sucrose gradient, the altered particle sediments at 135S, has lost the coat protein VP4, and has become more hydrophobic. Altered particles can be found...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
