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Article

A conditional-lethal murine coronavirus mutant that fails to incorporate the spike glycoprotein into assembled virions.

Virus research - 1 Dec 1995

Ricard C S, Koetzner C A, Sturman L S, Masters P S

Abstract excerpt

The coronavirus spike glycoprotein (S) mediates both the attachment of virus to the host cell receptor and membrane fusion. We describe here the characterization of a temperature-sensitive mutant of the coronavirus mouse hepatitis virus A59 (MHV-A59) having multiple S protein-related defects. The most remarkable of these was that the mutant, designated Albany 18 (Alb18), assembled virions devoid of the S...

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Identifiers

PMID: 8837889
DOI: 10.1016/0168-1702(95)00100-x
PMCID: PMC7134215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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