Article
Structural studies of poliovirus mutants that overcome receptor defects.
Nature structural biology - 1 Aug 1997
Wien M W, Curry S, Filman D J, Hogle J M
Abstract excerpt
In order to better understand the process of cell entry for non-enveloped viruses, we have solved the crystal structures of five poliovirus mutants which can infect cells expressing mutant poliovirus receptors. Four of these structures have been solved from frozen crystals using cryocrystallograp...
Topics
- Capsid
- Capsid Proteins
- Computer Simulation
- Crystallography, X-Ray
- Membrane Proteins
- Models, Molecular
- Molecular Conformation
- Mutation
- Phenotype
- Poliovirus
- Protein Binding
- Receptors, Virus