Efficient analysis of nonviable poliovirus capsid mutants.

doi:10.1128/JVI.67.3.1734-1738.1993

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Article

Efficient analysis of nonviable poliovirus capsid mutants.

Journal of virology - 1 Mar 1993

Simons J, Rogove A, Moscufo N, Reynolds C, Chow M

Abstract excerpt

Nonviable poliovirus capsid mutants were studied by an efficient infection-transfection system. Phenotypically, nonviable poliovirus capsid mutants appear to segregate into three classes: those that form only protomers, those that can form pentamers, and one that can form completed virions.

Topics

Capsid
Capsid Proteins
HeLa Cells
Humans
Mutagenesis, Site-Directed
Mutation
Myristic Acid
Myristic Acids
Neutralization Tests
Poliovirus
Protein Processing, Post-Translational
Transfection

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