Article
Mutagenic activity of ambient oxygen and mitomycin C in Fanconi's anaemia cells.
Mutagenesis - 1 Mar 1997
Liebetrau W, Rünger T M, Mehling B E, Poot M, Hoehn H
Abstract excerpt
Cellular evidence suggests that Fanconi's anaemia (FA) might be a condition of increased oxygen sensitivity. In order to test this hypothesis, a common shuttle vector assay with the plasmid pZ189 was utilized. We transfected intact, circular plasmid into FA and control lymphoblast and fibroblast host cells maintained at 5 and 20% O2 (v/v). In parallel experiments, host cells were exposed to different...
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