Article
Molecular analysis of mutations induced by acrolein in human fibroblast cells using supF shuttle vector plasmids.
Mutation research - 11 Sept 1998
Kawanishi M, Matsuda T, Nakayama A, Takebe H, Matsui S, Yagi T
Abstract excerpt
Types of mutations induced by acrolein in the supF gene on the shuttle vector plasmid pMY189 replicated in normal human fibroblast cells were examined. Base sequence analysis of 92 plasmids with mutations in the supF gene revealed that the majority of the mutations were base substitutions (76%) a...
Topics
- Acrolein
- Base Sequence
- Cell Line
- DNA Mutational Analysis
- Fibroblasts
- Humans
- Molecular Sequence Data
- Mutagenicity Tests
- Mutation
- Plasmids