Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis.

doi:10.1093/carcin/11.2.283

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Article

Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis.

Carcinogenesis - 1 Feb 1990

Moraes E C, Keyse S M, Tyrrell R M

Abstract excerpt

Hydrogen peroxide is an oxidizing agent which can be generated intracellularly either during normal metabolism or by treatment with external agents including solar UV radiation. Simian cells (CV-1) transfected with the SV40-based shuttle vector plasmid pZ189 have been treated with H2O2 and then i...

Topics

Animals
Base Composition
Base Sequence
Cell Line
Chromosome Deletion
DNA
Hydrogen Peroxide
Molecular Sequence Data
Mutation
Repetitive Sequences, Nucleic Acid

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