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Article

Carbon dioxide modulation of peroxynitrite-induced mutagenesis of the supF gene in pSP189.

Chemical research in toxicology - 1 Apr 2003

Pamir Burcak, Wogan Gerald N

Abstract excerpt

Peroxynitrite (ONOO(-)), a potent oxidant formed by the reaction of nitric oxide with superoxide anion, may play a significant role as an intermediate in NO(*)-related cytotoxicity and genotoxicity. In addition to causing other types of toxicity, peroxynitrite damages DNA and induces mutations in genetic targets following in vitro or in vivo exposure. It has recently been established that the reaction of CO(2)...

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Identifiers

PMID: 12703965
DOI: 10.1021/tx020093t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Carbon dioxide modulation of peroxynitrite-induced mutagenesis of the supF gene in pSP189.PMID 12703965Read ↗

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