Article
Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity.
Atherosclerosis - 21 Mar 1997
Galinsky D, Tysoe C, Brayne C E, Easton D F, Huppert F A, Dening T R, Paykel E S, Rubinsztein D C
Abstract excerpt
Genetic factors are likely to affect human survival, since twin studies have shown greater concordance for age of death in monozygotic compared to dizygotic twins. Coronary artery disease is an important contributor to premature mortality in the UK. Accordingly, we have chosen genes associated with cardiovascular risk, apo E/apo C-I, angiotensin converting enzyme (ACE) and methylenetetrahydrofolate reductase...
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