Article
Angiotensin converting enzyme gene, smoking and mortality in a population-based study.
European journal of clinical investigation - 1 Jul 2005
Arias-Vásquez A, Sayed-Tabatabaei F A, Schut A F C, Hofman A, Bertolli-Avella A M, Vergeer J M, Aulchenko Y S, Witteman J C M, van Duijn C M
Abstract excerpt
BACKGROUND: The genetic and environmental risk factors, which may influence longevity and mortality, have received much attention during more than one decade. One of the major risks for mortality is cardiovascular disease and the renin angiotensin system (RAS) plays a major role in maintaining blood pressure homeostasis. In this system, the Angiotensin Converting Enzyme (ACE) is one of the key regulators and has...
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