Article
Angiotensin converting enzyme insertion/deletion polymorphism in sporadic and familial Alzheimer's disease and longevity.
Archives of gerontology and geriatrics - 1 Jan 2000
Nacmias Benedetta, Bagnoli Silvia, Tedde Andrea, Cellini Elena, Bessi Valentina, Guarnieri Biancamaria, Ortensi Luigi, Piacentini Silvia, Bracco Laura, Sorbi Sandro
Abstract excerpt
A recent, large meta-analysis has reproposed the role of the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism as a risk factor for Alzheimer's disease (AD). To further investigate the proposed association and to better clarify the role of ACE as a risk factor for AD, we analyzed the genotype and allele frequency distribution of ACE I/D and apolipoprotein E (APOE) gene polymorphisms in 235...
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