Article
A study of French centenarians: are ACE and APOE associated with longevity?
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Feb 2001
Blanché H, Cabanne L, Sahbatou M, Thomas G
Abstract excerpt
Association study is the method of choice to identify genes involved in complex processes that result from the interaction of environmental and genetic factors. However, because of biases that increase the risk of false positive reports, preliminary positive conclusions have to be reproduced on other populations to be validated as firm conclusions. In 1994, certain alleles of two genes, APOE (Apolipoprotein E)...
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