Article
DNA multiallelic systems reveal gene/longevity associations not detected by diallelic systems. The APOB locus.
Human genetics - 1 Mar 1997
De Benedictis G, Falcone E, Rose G, Ruffolo R, Spadafora P, Baggio G, Bertolini S, Mari D, Mattace R, Monti D, Morellini M, Sansoni P, Franceschi C
Abstract excerpt
To identify possible genetic factors affecting human longevity we compared allele pools at two candidate loci for longevity between a sample of 143 centenarians (S) and a control sample of 158 individuals (C). The candidate loci were APOB and TPO, which code for apolipoprotein B and thyroid peroxidase, respectively. Both restriction fragment length (RFL) (XbaI2488 and EcoRI4154) and variable number of tandem...
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