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Article

Angiotensin I converting enzyme (ACE) gene polymorphism in centenarians: different allele frequencies between the North and South of Europe.

Experimental gerontology - 1 Sept 2003

Panza Francesco, Solfrizzi Vincenzo, D'Introno Alessia, Colacicco Anna Maria, Capurso Cristiano, Kehoe Patrick G, Capurso Antonio

Abstract excerpt

Variants of the angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (ACE1) gene and the apolipoprotein E gene (APOE) have been suggested to be associated with human longevity. We tested the association between the ACE1 insertion (I allele)/deletion (D allele) polymorphism and longevity in a population from Southern Italy and examined the impact of geographical variation on ACE1 allele frequencies on...

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Source

Identifiers

PMID: 12954489
DOI: 10.1016/s0531-5565(03)00154-2

Genes

APOE
ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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