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Article

Rap1 affects the length and heterogeneity of human telomeres.

Molecular biology of the cell - 1 Dec 2003

Li Bibo, de Lange Titia

Abstract excerpt

Telomere length is controlled in part by cis-acting negative regulators that limit telomere extension by telomerase. In budding yeast, the major telomere length regulator scRap1 binds to telomeric DNA and acts to inhibit telomere elongation in cis. Because the human Rap1 ortholog hRap1 does not b...

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Identifiers

PMID: 14565979
DOI: 10.1091/mbc.e03-06-0403
PMCID: PMC284807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14565979-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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