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Article

Yeast Rap1 contributes to genomic integrity by activating DNA damage repair genes.

The EMBO journal - 4 Jun 2008

Tomar Raghuvir S, Zheng Suting, Brunke-Reese Deborah, Wolcott Holly N, Reese Joseph C

Abstract excerpt

Rap1 (repressor-activator protein 1) is a multifunctional protein that controls telomere function, silencing and the activation of glycolytic and ribosomal protein genes. We have identified a novel function for Rap1, regulating the ribonucleotide reductase (RNR) genes that are required for DNA repair and telomere expansion. Both the C terminus and DNA-binding domain of Rap1 are required for the activation of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18480842
DOI: 10.1038/emboj.2008.93
PMCID: PMC2426730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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