Article
A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.
Genes & development - 1 May 1992
Hardy C F, Sussel L, Shore D
Abstract excerpt
The yeast RAP1 protein is a sequence-specific DNA-binding protein that functions as both a repressor and an activator of transcription. RAP1 is also involved in the regulation of telomere structure, where its binding sites are found within the terminal poly(C1-3A) sequences. Previous studies have indicated that the regulatory function of RAP1 is determined by the context of its binding site and, presumably, its...
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