Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length.

doi:10.1126/science.2237406

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Article

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length.

Science (New York, N.Y.) - 26 Oct 1990

Lustig A J, Kurtz S, Shore D

Abstract excerpt

The yeast protein RAP1, initially described as a transcriptional regulator, binds in vitro to sequences found in a number of seemingly unrelated genomic loci. These include the silencers at the transcriptionally repressed mating-type genes, the promoters of many genes important for cell growth, a...

Topics

Base Sequence
Binding Sites
Chromosomes, Fungal
DNA-Binding Proteins
Fungal Proteins
Genes, Fungal
Genes, Mating Type, Fungal
Molecular Sequence Data
Mutation
Plasmids
Poly A
Poly C
Repetitive Sequences, Nucleic Acid
Saccharomyces cerevisiae
Temperature
Transcription Factors
Transformation, Genetic

Source

Open in PubMed

Identifiers

PMID: 2237406
DOI: 10.1126/science.2237406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2237406-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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