Article
Genetic analysis of Rap1p/Sir3p interactions in telomeric and HML silencing in Saccharomyces cerevisiae.
Genetics - 1 May 1996
Liu C, Lustig A J
Abstract excerpt
We have identified three SIR3 suppressors of the telomeric silencing defects conferred by missense mutations within the Rap1p C-terminal tail domain (aa 800-827). Each SIR3 suppressor was also capable of suppressing a rap1 allele (rap1-21), which deletes the 28 aa C-terminal tail domain, but none...
Topics
- Alleles
- Binding Sites
- Chromosomes, Fungal
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Genotype
- Mating Factor
- Peptide Biosynthesis
- Peptides
- Restriction Mapping
- Saccharomyces cerevisiae
- Silent Information Regulator Proteins, Saccharomyces cerevisiae
- Suppression, Genetic
- Telomere
- Trans-Activators
- Transcription Factors
- Transcription, Genetic