Article
Increased apolipoprotein E epsilon 4 in epilepsy with senile plaques.
Annals of neurology - 1 Mar 1997
Gouras G K, Relkin N R, Sweeney D, Munoz D G, Mackenzie I R, Gandy S
Abstract excerpt
Inheritance of the apolipoprotein E (ApoE) epsilon 4 allele is a risk factor for Alzheimer's disease (AD) and is associated with increased deposition of beta-amyloid (A beta) in AD, Down's syndrome, and normal aging. A beta deposition in the form of senile plaques (SPs) has recently been described in patients with temporal lobe epilepsy (TLE). We studied the relationship between ApoE epsilon 4 genotype and the...
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