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Article

Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease.

Annals of neurology - 1 Jan 1996

Gomez-Isla T, West H L, Rebeck G W, Harr S D, Growdon J H, Locascio J J, Perls T T, Lipsitz L A, Hyman B T

Abstract excerpt

Inheritance of the apolipoprotein E (apoE) epsilon 4 allele is associated with a high likelihood of developing Alzheimer's disease (AD). The pathophysiologic basis of this genetic influence is unknown. We reasoned that understanding the influence of apoE epsilon 4 on the clinical course and neuropathological features of AD may provide tests of potential mechanisms. We carried out a prospective longitudinal study...

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Identifiers

PMID: 8572669
DOI: 10.1002/ana.410390110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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