Article
The apolipoprotein E epsilon 4 allele is not associated with early onset temporal lobe epilepsy.
Neuroreport - 24 Mar 1997
Blümcke I, Brockhaus A, Scheiwe C, Rollbrocker B, Wolf H K, Elger C E, Wiestler O D
Abstract excerpt
A polymorphism of the apolipoprotein E gene, in particular the epsilon 4 allele (ApoE4), has been associated with impaired neuronal phospholipid metabolism and synapse reorganization and has been implicated in several neurodegenerative disorders. Since selective neuronal cell lose and aberrant axonal reorganization represent hall-marks of Ammon's horn sclerosis (AHS) in patients with chronic temporal lobe...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
