Article
ApoE epsilon4 genotype and the age at onset of temporal lobe epilepsy: a case-control study and meta-analysis.
Epilepsy research - 1 Aug 2010
Kauffman Marcelo Andrés, Consalvo Damián, Moron Dolores Gonzalez, Lereis Virginia Pujol, Kochen Silvia
Abstract excerpt
In order to investigate the role of ApoE epsilon4 as a modifier of the age at onset of temporal lobe epilepsy (TLE), we performed a molecular epidemiology study in 78 patients with mesial temporal lobe epilepsy and hippocampal sclerosis. Genotyping was done by a PCR-RFLP assay. In order to better estimate the role of this variant as a modifier of the age at onset, we also performed a systematic review of the...
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