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Article

Apolipoprotein E genotype and deposits of Abeta40 and Abeta42 in Alzheimer disease.

Archives of neurology - 1 Jul 1998

McNamara M J, Gomez-Isla T, Hyman B T

Abstract excerpt

OBJECTIVE: To examine the differential deposition of amyloid beta (Abeta) peptide isoforms Abeta40 and Abeta42 in the Alzheimer disease (AD) brain in relation to the apolipoprotein E (APOE) genotype. BACKGROUND: The APOE epsilon4 genotype is an inherited risk factor for AD and is associated with increased deposition of Abeta protein in the cerebral cortex. Previous data from familial AD due to mutations in...

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Identifiers

PMID: 9678319
DOI: 10.1001/archneur.55.7.1001

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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