Association of apolipoprotein epsilon 4 allele and neuropathologic findings in patients with dementia.

doi:10.1007/BF00296506

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Article

Association of apolipoprotein epsilon 4 allele and neuropathologic findings in patients with dementia.

Acta neuropathologica - 1 Jan 1995

Martinoli M G, Trojanowski J Q, Schmidt M L, Arnold S E, Fujiwara T M, Lee V M, Hurtig H, Julien J P, Clark C

Abstract excerpt

Apolipoprotein E (APOE) is a lipoprotein expressed in liver and brain as one of three isoforms (APOE 2, APOE 3 and APOE 4). Recent findings suggest that the presence of APOE 4 is associated with an increased risk for both familial Alzheimer's disease and late-onset Alzheimer's disease. We extende...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Dementia
Genotype
Humans
Middle Aged

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