Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E allele epsilon 4 is linked to increased deposition of the amyloid beta-peptide (A-beta) in cases with or without Alzheimer's disease.

Neuroscience letters - 12 Sept 1994

Berr C, Hauw J J, Delaère P, Duyckaerts C, Amouyel P

Abstract excerpt

To assess the significance of the association between apolipoprotein E (APOE) epsilon 4 allele and amyloid beta-peptide (A-beta) deposits in the brain, we performed APOE-genotyping and measured the density of A-beta deposits, neuritic plaques and neurofibrillary tangles in 27 cases from the Charles Foix clinico-pathological prospective study. We found an increased density of A-beta deposits in the three cases...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Amyloid beta-Peptides
Apolipoproteins E
Brain
Female
Genotype
Heterozygote
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prospective Studies

Reference Values

Source

Identifiers

PMID: 7824200
DOI: 10.1016/0304-3940(94)90763-3

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7824200-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E allele epsilon 4 is linked to increased deposition of the amyloid beta-peptide (A-beta) in cases with or without Alzheimer's disease.PMID 7824200Read ↗

ApoE epsilon 4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis.Semantic proximity Read ↗

Alzheimer pathology of patients carrying apolipoprotein E epsilon 4 allele.Semantic proximity Read ↗

Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease.Semantic proximity Read ↗

The apolipoprotein E allele epsilon 4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein-E genotyping in Alzheimer's disease and frontotemporal dementia.Semantic proximity Read ↗

ApoE epsilon 4 allele and cognitive decline in patients with Alzheimer's disease.Semantic proximity Read ↗

Alzheimer's disease and the apolipoprotein E epsilon 4 allele.Semantic proximity Read ↗

APOE epsilon 4 allele frequency in Alzheimer's disease and vascular dementia in the Spanish population.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 in an autopsy series of various dementing disorders.Semantic proximity Read ↗

Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies.Semantic proximity Read ↗

Apolipoprotein E, dementia, and cortical deposition of beta-amyloid protein.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.