Article
The influence of factor VIII on measurement of activated protein C resistance.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Nov 1996
Laffan M A, Manning R
Abstract excerpt
Activated protein C resistance (APCR) has proved to be a frequent finding in association with thrombosis. The majority of patients with APCR have been found to be homozygous or heterozygous for the polymorphic variant factor V Q506 (factor V Leiden; FVQ506). However a small number of patients have APCR as assessed by functional tests but do not possess the FVQ506 polymorphism. Some of these cases are due to the...
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