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Article

A comparison between two activated protein C resistance methods as routine diagnostic tests for factor V Leiden mutation.

British journal of haematology - 1 Jun 1997

Aboud M R, Ma D D

Abstract excerpt

The most common commercially available test measuring activated protein C (APC) resistance relies on the the anticoagulant response to added APC in an activated partial thromboplastin time (APTT) based method. Another method is a Russell Viper venom time (RVVT) based system. To improve the specificity for factor V Leiden of the APTT based method, pre-dilution of test plasma in FV-deficient plasma has recently...

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Source

Identifiers

PMID: 9217178
DOI: 10.1046/j.1365-2141.1997.1432958.x

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

A comparison between two activated protein C resistance methods as routine diagnostic tests for factor V Leiden mutation.PMID 9217178Read ↗

Whole blood screening test for factor V Leiden using a Russell viper venom time-based assay.Semantic proximity Read ↗

Comparison of an activated partial thromboplastin time with a Russell viper venom time test in screening for factor V(Leiden) (FVR506Q).Semantic proximity Read ↗

Careful selection of sample dilution and factor-V-deficient plasma makes the modified activated protein C resistance test highly specific for the factor V Leiden mutation.Semantic proximity Read ↗

Determination of activated protein C resistance in anticoagulated and lupus positive patients.Semantic proximity Read ↗

Comparison of three activated protein C resistance tests in the risk assessment of venous thrombosis in non-carriers of the factor V Leiden mutation.Semantic proximity Read ↗

Activated protein C resistance assay detects thrombotic risk factors other than factor V Leiden.Semantic proximity Read ↗

Laboratory Testing for the Evaluation of Phenotypic Activated Protein C Resistance.Semantic proximity Read ↗

Use of modified functional assays for activated protein C resistance in patients with basally prolonged aPTT.Semantic proximity Read ↗

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Coagulation assay with improved specificity to factor V mutants insensitive to activated protein C.Semantic proximity Read ↗

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