Use of modified functional assays for activated protein C resistance in patients with basally prolonged aPTT.

Article

Use of modified functional assays for activated protein C resistance in patients with basally prolonged aPTT.

Thrombosis and haemostasis - 1 Sept 1997

Montaruli B, Schinco P, Pannocchia A, Giorgianni A, Borchiellini A, Tamponi G, Pileri A

Abstract excerpt

Inherited resistance to activated protein C (APCr) is currently recognized as the most prevalent cause underlying venous thrombophilia, with an estimated prevalence around 20% in thrombotic patients and around 1.8-7% in the general population. A correct laboratory diagnosis of APCr is therefore e...

Topics

Adult
Blood Coagulation Tests
Factor V
Female
Humans
Male
Middle Aged
Mutation
Partial Thromboplastin Time
Protein C
Reagent Kits, Diagnostic
Sequence Analysis, DNA

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