Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of platelet phospholipid exposure on activated protein C resistance: implications for thrombophilia screening.

British journal of haematology - 1 Mar 1996

Luddington R, Brown K, Baglin T

Abstract excerpt

The effect of platelet contamination and freeze-thawing on the activated protein C sensitivity ratio (APCsr) was determined. With increasing platelet count there was a progressive reduction in the ratio. Filtration of samples through a 0.2 microm filter before or after freeze-thawing abolished the development of resistance to the addition of activated protein C indicating that the phenomenon is due to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Blood Platelets
Share to APC gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Phospholipids

Share to Protein C

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 8616047
DOI: 10.1046/j.1365-2141.1996.391924.x

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Effect of platelet phospholipid exposure on activated protein C resistance: implications for thrombophilia screening.PMID 8616047Read ↗

Studies on phospholipid antibodies, APC-resistance and associated mutation in the coagulation factor V gene.Semantic proximity Read ↗

Production of phospholipid antibodies in selected thrombophilic women differing in genotype at the 506 site of factor V.Semantic proximity Read ↗

Standardization of activated protein C resistance testing: effect of residual platelets in frozen plasmas assessed by commercial and home-made methods.Semantic proximity Read ↗

The influence of factor VIII on measurement of activated protein C resistance.Semantic proximity Read ↗

Congenital resistance to activated protein C in patients with lupus anticoagulants: evaluation of two functional assays.Semantic proximity Read ↗

Impact of oral contraceptive use on APC-resistance: a prospective, randomized clinical trial with three low-dose preparations.Semantic proximity Read ↗

The use of two different APC resistance assay systems provides optimal sensitivity and specificity for diagnosing genetic APC resistance.Semantic proximity Read ↗

Resistance to activated protein C, associated with oral contraceptives use; effect of formulations, duration of assumption, and doses of oestro-progestins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.