Article
A chromogenic assay for activated protein C resistance.
British journal of haematology - 1 Aug 1995
Váradi K, Moritz B, Lang H, Bauer K, Preston E, Peake I, Rivard G E, Keil B, Schwarz H P
Abstract excerpt
Resistance to activated protein C (APC) diagnosed on the basis of prolongation of clotting time in an activated partial thromboplastin time (aPTT) assay is now considered a major cause of inherited thrombophilia. The majority of patients with APC resistance carry a factor V molecule with a point...
Topics
- Anticoagulants
- Blood Coagulation
- Chromogenic Compounds
- Factor V
- Factor VIII
- Factor Va
- Female
- Humans
- Male
- Mutation
- Protein C
- Reference Values