Article
Determination of activated protein C resistance in anticoagulated and lupus positive patients.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2000
Ivey L M, Thom J Y, Ivey J G, Baker R I
Abstract excerpt
Clotting-based activated protein C (APC) assays have limitations when testing patients on oral anticoagulant (OA) therapy or with a lupus anticoagulant (LA). Predilution in factor V (FV)-deficient plasma and testing with phospholipid-rich Russell Viper venom (RVV)-based methods have been shown to be the most suitable methods when testing these patient groups, respectively. We evaluated a modified RVV based...
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