Article
The impact of oral anticoagulant therapy, factor VIII level and quality of factor V-deficient plasma on three commercial methods for activated protein C resistance.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2001
Chitolie A, Lawrie A S, Mackie I J, Harrison P, Machin S J
Abstract excerpt
Several methods are now available for the laboratory assessment of activated protein C resistance (APCR). In this study, we evaluated two activated partial thromboplastin time-based assays [Coatest activated protein C (APC) and Diagen protein C activator (PCA)], with and without predilution of test plasma in factor V-deficient plasma (FVdp) and an amidolytic assay (Immuno Ltd, Vienna, Austria). Testing plasmas...
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