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Article

Resistance to activated protein C and low levels of protein S activity in nine thrombophilic families: a correct diagnosis.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 1997

Gemmati D, Serino M L, Verzola I, Mari R, Moratelli S, Ballerini G

Abstract excerpt

In order to define the thrombophilic conditions related to activated protein C resistance (APC-R) and protein S (PS) deficiency and to detect the possible combination of these defects, we studied nine unrelated patients selected because of low anticoagulant response to APC and reduced PS activity with at least one first degree relative having the same coagulation feature. The mean APC ratio was 0.64 (normal...

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Source

Identifiers

PMID: 9518043
DOI: 10.1097/00001721-199703000-00006

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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