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Article

A modification of the APC resistance test and its application to the study of patients on coumarin therapy.

Thrombosis research - 1 May 1996

Jorquera J I, Aznar J, Fernández M A, Montoro J M, Curats R, Casaña P

Abstract excerpt

APC resistance appears to be caused, predominantly, by a mutation in coagulation factor V (nucleotide 1691: G to A). This phenomenon is usually studied by performing APTTs in the absence and presence of added APC. We studied a modification of the assay involving dilution of the test plasma in fac...

Topics

Adult
Aged
Aged, 80 and over
Anticoagulants
Case-Control Studies
Coumarins
Drug Resistance
Factor V Deficiency
Humans
Middle Aged
Mutation
Protein C
Thrombophlebitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8732625
DOI: 10.1016/0049-3848(96)00068-0

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8732625-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A modification of the APC resistance test and its application to the study of patients on coumarin therapy.PMID 8732625Read ↗

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