Article
Ornithine decarboxylase and polyamines in familial adenomatous polyposis.
Cancer research - 15 Jan 1997
Giardiello F M, Hamilton S R, Hylind L M, Yang V W, Tamez P, Casero R A
Abstract excerpt
Familial adenomatous polyposis (FAP), due to germ-line mutation of the adenomatous polyposis coli (APC) gene, is characterized by development of colorectal adenomas and ultimately colorectal cancer. The usefulness of ornithine decarboxylase (ODC) activity and polyamine levels in normal-appearing colorectal mucosa to stratify risk for colorectal neoplasia by discriminating presymptomatic individuals with germ-line...
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