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Article

Dietary polyamine intake and risk of colorectal adenomatous polyps.

The American journal of clinical nutrition - 1 Jul 2012

Vargas Ashley J, Wertheim Betsy C, Gerner Eugene W, Thomson Cynthia A, Rock Cheryl L, Thompson Patricia A

Abstract excerpt

BACKGROUND: Putrescine, spermidine, and spermine are the polyamines required for human cell growth. The inhibition of ornithine decarboxylase (ODC), which is the rate-limiting enzyme of polyamine biosynthesis, decreases tumor growth and the development of colorectal adenomas. A database was developed to estimate dietary polyamine exposure and relate exposure to health outcomes. OBJECTIVE: We hypothesized that...

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Identifiers

PMID: 22648715
DOI: 10.3945/ajcn.111.030353
PMCID: PMC3374737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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