Article
Genetic and biochemical changes in colorectal carcinoma in relation to morphologic characteristics.
Oncology reports - 1 Jan 2000
Notarnicola Maria, Linsalata Michele, Caruso Maria Gabriella, Caruso Maria Lucia, Altomare Donato, Lorusso Dionigi, Leo Silvana, Di Leo Alfredo
Abstract excerpt
A distinct genetic pathway may be involved in the development of polypoid and flat colorectal cancers, two morphologically different cancer subtypes. The present study was undertaken to clarify whether different combinations of some genetic alterations commonly involved (such as K-ras and p53 gene mutations) may exist between polypoid and flat types. In addition, to investigate any different proliferative...
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