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Article

Variants downstream of the ornithine decarboxylase gene influence risk of colorectal adenoma and aspirin chemoprevention.

Cancer prevention research (Philadelphia, Pa.) - 1 Dec 2011

Barry Elizabeth L, Mott Leila A, Sandler Robert S, Ahnen Dennis J, Baron John A

Abstract excerpt

Increased mucosal polyamine levels and ornithine decarboxylase (ODC) activity are associated with an increased risk of colorectal neoplasia and aspirin treatment reduces risk. Previous studies suggest that a single-nucleotide polymorphism (SNP) in the promoter of the ODC gene (rs2302615) may be a...

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Identifiers

PMID: 21930798
DOI: 10.1158/1940-6207.CAPR-11-0300
PMCID: PMC3232321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21930798-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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