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Article

A test for neutrality of mutations of the lacZ transgene.

Environmental and molecular mutagenesis - 1 Jan 1996

Cosentino L, Heddle J A

Abstract excerpt

Neutral mutations are stable alterations in DNA that are neither beneficial nor damaging to the cell. Once a mutation is fixed in the DNA, the mutant frequency should increase to its maximum and plateau thereafter, provided that enough expression time is given. Evidence has been obtained indicating neutrality for the endogenous Dlb-1 locus and for the lacl in the BigBlue transgenic system, and is reported here...

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Source

Identifiers

PMID: 8991058
DOI: 10.1002/(SICI)1098-2280(1996)28:4<313::AID-EM3>3.0.CO;2-C

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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